Atypical
Fibroxanthoma.
Rare skin cancer of the elderly.
Rare skin cancer of the elderly.
Atypical Fibroxanthoma (AFX) is a rare Skin Tumour that occurs in response to UV light.
Think of Atypical Fiboxanthoma (AFX) in an older fair-skinned man with an enlarging nodule on the head or neck.
The appearance is not specific and, particularly when scaly, may look like squamous cell carcinoma.
The final diagnosis is made by expert pathological examination of a good quality, deep biopsy sample. Diagnosis is not straightforward, and special stains are often required to distinguish the AFX from ‘undifferentiated pleomorphic sarcoma’ (UPS).
The tumor is low grade but does require surgical excision with wide margins to keep the rate of recurrence to a minimum.
Mohs surgery is an additional option.
Gallery of Fibroxanthoma
Please click on the images for details.
Atypical Fibroxanthoma may be diagnosed late for these reasons:
AFX is a significant skin cancer in that treatment is more challenging than SCC or BCC.
Metastases (distance spread) occurs in 0.5% to 4% of cases.
Atypical fibroxanthoma is a rare Skin Cancer.
REFERENCES
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